A Chronic Skin Condition That Needs More Awareness (and Better Treatments)

hidradenitis suppurativa

Hidradenitis Suppurativa, or HS for short, is a chronic skin condition that many people have never heard of—but for those who live with it, the impact can be both physically and emotionally exhausting. HS causes painful lumps to form under the skin, typically in areas where skin rubs together—like the armpits, groin, buttocks, and under the breasts. These lumps can swell, rupture, drain pus, and leave behind deep scars. For many, it feels like a never-ending cycle of flare-ups, infections, and discomfort that seriously interferes with daily life.

What makes HS especially frustrating is that it’s not caused by poor hygiene, and it’s not contagious. It’s actually a chronic inflammatory skin condition that occurs when hair follicles become blocked and inflamed, likely due to a combination of genetic, hormonal, and immune system factors. HS often begins after puberty and is more common in women than men. It can range from mild (occasional painful bumps) to severe (widespread abscesses and tunneling wounds called sinus tracts), making it difficult for patients to find relief.

Unfortunately, HS is frequently misdiagnosed as boils or infections, which delays proper treatment. The exact cause is still being studied, but we do know that factors like smoking, obesity, and family history can increase the risk of developing the disease. HS also tends to run in families, suggesting a genetic link.

When it comes to treatment, options have historically been limited. Doctors may prescribe antibiotics, anti-inflammatory medications, hormonal treatments, or even biologic drugs that target the immune system. In more advanced cases, surgery may be needed to remove damaged tissue. But even with treatment, many patients experience recurring flare-ups and long-term scarring. That’s why new treatments are urgently needed—and clinical trials are playing a major role in finding them.

At Physicians Research Group (PRG), we’re proud to be helping change the future of HS care. Our research sites are currently conducting clinical trials focused on innovative therapies designed to reduce inflammation, prevent flare-ups, and promote healing. These investigational treatments include next-generation biologics, topical therapies, and oral medications that aim to target HS at the root cause rather than just managing the symptoms. Participants in our trials may gain early access to these cutting-edge therapies under close medical supervision—often at no cost.

By joining a clinical trial with PRG, patients have the opportunity to receive advanced care while contributing to research that could change how HS is treated for future generations. We understand how difficult living with this condition can be, and we are committed to making sure every participant feels supported, informed, and empowered throughout their journey.

If you or someone you know is struggling with hidradenitis suppurativa and wants to explore new treatment options, consider participating in a clinical trial with PRG. Visit www.prgresearch.com to learn more about current HS studies and see if you qualify. Together, we can improve care and bring hope to those living with this painful condition.