Upcoming Studies
Explore clinical research opportunities focused on evaluating treatment approaches across a range of health conditions.
Clinical Trials at Physicians Research Group
At Physicians Research Group, we conduct clinical research in accordance with established medical, ethical, and regulatory standards. Our upcoming studies focus on evaluating new and existing treatment approaches across a range of health conditions, with an emphasis on participant safety and careful monitoring. Participation in clinical research supports the collection of data used to better understand medical treatments in controlled study settings.
Each study follows approved protocols and ethical guidelines to help ensure accurate and reliable research findings.
Our Upcoming Studies
Arizona
Physicians Research Group is conducting an upcoming clinical study evaluating the safety and effectiveness of an investigational, minimally invasive procedure designed to help restore ovulation in women with infertility related to PCOS. This study is intended for women who are actively trying to conceive and have not had success with standard fertility treatments or prefer alternative options.
Participants will undergo a specialized ultrasound-guided procedure and will be monitored over time to assess ovulation, hormonal changes, and overall safety outcomes. The goal of this research is to explore new treatment approaches that may improve fertility outcomes and expand future options for women living with PCOS.
Infertility Due to Polycystic Ovary Syndrome (PCOS)
Eligibility Criteria
Status
Upcoming / Enrolling Soon
Age
18 – 40 years
Condition
Polycystic Ovary Syndrome (PCOS)
Location
Arizona
Gender
Female
Diabetic Foot Ulcers
Diabetic foot ulcers are open sores or wounds that develop on the feet of individuals living with diabetes, often caused by poor circulation and nerve damage. These ulcers can be slow to heal, painful, and difficult to manage, increasing the risk of infection and serious complications.
Physicians Research Group is conducting a clinical trial to evaluate the safety and effectiveness of an investigational therapy used alongside standard wound care in adults with chronic diabetic foot ulcers. The goal of this study is to determine whether the treatment can improve healing outcomes, promote faster closure of wounds, and provide a safer, more effective approach for patients whose ulcers have not responded to conventional care.
Eligibility Criteria
Age
18 years and older
Condition
Diabetic Foot Ulcers
Location
Arizona
Gender
Male & Female
Status
Upcoming / Enrolling Soon
Knee Osteoarthritis and Cartilage Lesions
Knee osteoarthritis is a common joint condition where the protective cartilage in the knee gradually wears down. This can lead to pain, stiffness, swelling, and difficulty walking, climbing stairs, or performing daily activities. Cartilage damage can worsen symptoms over time and limit mobility, especially when standard treatments like physical therapy, pain medications, or injections no longer provide enough relief.
Physicians Research Group is conducting a Phase 3 clinical trial to evaluate the safety and effectiveness of an investigational treatment approach compared to a standard surgical procedure in adults with knee cartilage damage and osteoarthritis. The goal of this study is to determine whether the investigational approach can provide better long-term pain relief, improve knee function, and support cartilage repair compared to standard care alone.
Eligibility Criteria
Age
18–75 years
Condition
Knee Osteoarthritis with Cartilage Damage
Gender
Female
Status
Upcoming / Enrolling Soon
Osteomyelitis (Bone Infection)
Physicians Research Group is conducting a clinical trial to evaluate a new approach to treating osteomyelitis following surgery to remove infected bone. The study will assess the safety and effectiveness of a treatment designed to help eliminate infection while supporting the body's natural bone healing process. Researchers hope this approach may reduce the risk of the infection returning and improve recovery for individuals living with bone infections.
Eligibility Criteria
Age
18 years and older
Condition
Osteomyelitis
Gender
Male & Female
Status
Upcoming / Enrolling Soon
Atopic Dermatitis (Eczema)
Atopic dermatitis is a chronic inflammatory skin condition that causes the skin barrier to become dry, irritated, and prone to flare-ups. It most commonly affects the face, hands, and the folds of the elbows and knees, and can cause symptoms such as intense itching, redness, dry or scaly patches, thickened skin, and open sores from scratching. Without proper treatment, the condition can disrupt sleep, damage the skin barrier further, and significantly impact daily quality of life.
Physicians Research Group is conducting a clinical trial to evaluate a new injectable treatment for moderate-to-severe atopic dermatitis. The study will assess the safety and effectiveness of the treatment compared to placebo, including whether it can be given less frequently over time while continuing to control symptoms. Researchers hope this approach may offer lasting relief from itching and skin inflammation for individuals living with eczema.
Eligibility Criteria
Age
12 years and older
Condition
Atopic Dermatitis (Eczema)
Gender
Male & Female
Status
Upcoming / Enrolling Soon
Osteoarthritis of the Knee
Osteoarthritis of the knee is a common joint condition that occurs when the protective cartilage cushioning the knee joint gradually wears down over time. It most commonly affects older adults and can cause symptoms such as persistent knee pain, stiffness, swelling, and reduced range of motion, making everyday activities like walking, climbing stairs, or standing up difficult. Without proper treatment, the condition can worsen over time and significantly limit mobility and quality of life.
Physicians Research Group is conducting a clinical trial to evaluate a new single-injection treatment for painful knee osteoarthritis. The study will assess the safety and tolerability of two different doses of the treatment, given directly into the knee, compared to placebo. Researchers hope this approach may help reduce knee pain and improve joint function over time, potentially offering longer-lasting relief than current treatment options.
Eligibility Criteria
Age
45-80 years
Condition
Osteoarthritis of the Knee
Gender
Male & Female
Status
Upcoming / Enrolling Soon
Distal subungual onychomycosis is a common fungal infection that affects the toenails, occurring when fungi invade the nail bed and nail plate. It most commonly affects the toenails and can cause symptoms such as nail thickening, discoloration (yellow, white, or brown), brittleness, crumbling edges, and separation of the nail from the nail bed. Without proper treatment, the infection can spread to other nails, worsen over time, and cause discomfort or difficulty with footwear.
Physicians Research Group is conducting a clinical trial to evaluate a topical treatment for moderate-to-severe toenail fungal infections. The study will assess how the treatment is absorbed by the body, along with its safety and tolerability, when applied daily to the toenails for a set period of time. Researchers hope this approach may offer an effective topical option for clearing stubborn nail fungus without the need for oral medication.
Toenail Fungal Infection (Distal Subungual Onychomycosis)
Eligibility Criteria
Age
18-65 years
Condition
Toenail Fungal Infection (Onychomycosis)
Gender
Male & Female
Status
Upcoming / Enrolling Soon
Cartilage damage in the ankle occurs when the smooth tissue cushioning the ankle joint becomes worn, torn, or damaged, often from injury or repeated stress. It most commonly affects the talus, a bone at the top of the ankle joint, and can cause symptoms such as persistent ankle pain, swelling, stiffness, and difficulty with activities like walking, running, or standing for long periods. Without proper treatment, the damage can worsen over time and lead to long-term joint problems.
Physicians Research Group is conducting a clinical trial to evaluate a cartilage repair procedure that uses a patient's own cells to help regenerate healthy cartilage in the ankle. The study will compare this approach to a standard surgical technique (bone marrow stimulation) to see which is more effective at relieving pain and restoring joint function. Researchers hope this approach may offer a longer-lasting solution for people with ankle cartilage damage that hasn't improved with other treatments.
Cartilage Damage in the Ankle (Chondral/Osteochondral Defects)
Eligibility Criteria
Age
17-65 years
Condition
Cartilage Damage of the Ankle
Gender
Male & Female
Status
Upcoming / Enrolling Soon
Massachusetts
Psoriasis Treatment Registry
The CorEvitas Psoriasis Registry invites patients in North America to help researchers study the safety and effectiveness of approved psoriasis treatments. Its main focus is on monitoring side effects, including serious events like cancer, especially in patients using new biologic therapies. Beyond safety, the registry also collects information on how psoriasis develops over time, other health conditions that often occur alongside psoriasis, and the treatments dermatologists use in real-world practice. By comparing outcomes across different therapies, the registry allows doctors to understand which treatments work best while providing valuable insights into the disease, its progression, and patient care.
Eligibility Criteria
Age
18 Years and older
Condition
Psoriasis
Location
Massachusetts
Gender
Male & Female
Status
Upcoming / Enrolling Soon
Colorado
Atopic dermatitis is a chronic inflammatory skin condition that causes the skin barrier to become dry, irritated, and prone to flare-ups. It most commonly affects the face, hands, and the folds of the elbows and knees, and can cause symptoms such as intense itching, redness, dry or scaly patches, thickened skin, and open sores from scratching. Without proper treatment, the condition can disrupt sleep, damage the skin barrier further, and significantly impact daily quality of life.
Physicians Research Group is conducting a clinical trial to evaluate a new oral treatment for moderate-to-severe atopic dermatitis. The study will assess how different doses of the treatment compare to placebo, tracking changes in skin symptoms and monitoring safety and tolerability over a 12-week treatment period. Researchers hope this approach may offer a convenient, effective option for people whose eczema has not responded well to other treatments.
Atopic Dermatitis (Eczema): (Corvus Pharmaceuticals)
Eligibility Criteria
Age
18 years and older
Condition
Atopic Dermatitis (Eczema)
Gender
Male & Female
Status
Upcoming / Enrolling Soon
Atopic dermatitis is a chronic inflammatory skin condition that causes the skin barrier to become dry, irritated, and prone to flare-ups. It most commonly affects the face, hands, and the folds of the elbows and knees, and can cause symptoms such as intense itching, redness, dry or scaly patches, thickened skin, and open sores from scratching. Without proper treatment, the condition can disrupt sleep, damage the skin barrier further, and significantly impact daily quality of life.
Physicians Research Group is conducting a clinical trial to evaluate a new injectable treatment for adults with moderate-to-severe atopic dermatitis who haven't responded well to topical treatments. The study will compare different dosing schedules of the treatment to placebo over the course of up to 48 weeks. Researchers hope this approach may offer longer-lasting symptom control with less frequent dosing than currently available treatment options.
Atopic Dermatitis (Eczema): (Inmagene)
Eligibility Criteria
Age
18-74 years
Condition
Atopic Dermatitis (Eczema)
Gender
Male & Female
Status
Upcoming / Enrolling Soon
Atopic dermatitis is a chronic inflammatory skin condition that causes the skin barrier to become dry, irritated, and prone to flare-ups. It most commonly affects the face, hands, and the folds of the elbows and knees, and can cause symptoms such as intense itching, redness, dry or scaly patches, thickened skin, and open sores from scratching. Without proper treatment, the condition can disrupt sleep, damage the skin barrier further, and significantly impact daily quality of life.
Physicians Research Group is conducting a clinical trial to evaluate a new injectable treatment for moderate-to-severe atopic dermatitis. The study will assess the safety and effectiveness of the treatment compared to placebo, including whether it can be given less frequently over time while continuing to control symptoms. Researchers hope this approach may offer lasting relief from itching and skin inflammation for individuals living with eczema.
Atopic Dermatitis (Eczema): (Nektar Therapeutics)
Eligibility Criteria
Age
12 years and older
Condition
Atopic Dermatitis (Eczema)
Gender
Male & Female
Status
Upcoming / Enrolling Soon
Indiana
Schizophrenia
Schizophrenia is a chronic mental health condition that affects how a person thinks, feels, and perceives reality. It can cause symptoms such as hallucinations, delusions, disorganized thinking, and reduced motivation or emotional expression, which can significantly disrupt daily functioning and relationships. Without ongoing treatment, symptoms can worsen or return, often leading to relapse and hospitalization.
Physicians Research Group is conducting a clinical trial to evaluate a long-acting injectable treatment for schizophrenia, given once a month, in helping prevent symptoms from returning. The study will compare continued treatment to placebo in patients whose symptoms are currently stable, to see how well the treatment maintains that stability over time. Researchers hope this approach may offer a more convenient, longer-lasting option for people managing schizophrenia, reducing the risk of relapse.
Eligibility Criteria
Age
18-65 years
Condition
Schizophrenia
Location
Indiana
Gender
Male & Female
Status
Upcoming / Enrolling Soon